As of 2014, he is 6'6'' tall and weighs about 275 pounds.
Oparei has had a diverse career. After a small supporting role in Alien 3 (1992), he has stated that he spent much of the 1990's as a drag queen street performer and "rent boy" (male prostitute). In 2002 he wrote and starred in a semi-autobiographical stage play about his experiences, Crazyblackmuthafuckin'self. The main character of the play is leading a triple life: by day, he is known as Femi, a studious, serious heterosexual black actor, son of Jehovah's Witnesses, and starring in a production of Othello; but by night, he slips into two alternate personas. Sometimes he is a "terrifying macho rent boy", tall and muscular, going by the name of "Big Black Jungle Nigga". Other nights, he adopts the persona of "Shaneequa", a transsexual, pre-op call girl, whose drag outfit consists of six inch high heels and tiny hot pants. London's The Daily Telegraph gave the play a very positive review, and praised both Oparei's writing and his acting versatility.
DeObia's first big break came with a small part in the 2002 film Moulin Rouge!, after which he entered into a steady film career, with roles in Doom, Mr. Nice, Your Highness, and Pirates of the Caribbean: On Stranger Tides. His most recent notable role was in the 2012 film Dredd, in which he played TJ the Paramedic.