Pyke may refer to:
- Pyke (island), one of the seven islands that make up the Iron Islands.
- Pyke (castle), the seat of House Greyjoy and capital of the Iron Islands: a castle which is situated on the island also named Pyke.
- "Pyke" is the bastard surname used in the Iron Islands, just as "Snow" is the bastard surname used in the North. It is not clear if it refers to the castle or the island (or both).
- Cotter Pyke, a bastard of the Iron Islands.